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$180.00 – $480.00
Imprints: “D 37” “W” “4172 V”
Shape/Color: Round White Tablets
Manufacturers: Sanofi-aventis U.S. LLC, Qualitest.
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Canada: 2 to 3 Days
International Delivery: 3 to 5 Days
To treat your moderate to severe pain.
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Dosage and Administration
DOSAGE FORMS AND STRENGTHS
Tablets: 50 mg and 100 mg.
Oral Solution: 50mg/5mL (10 mg/mL)
Ensure accuracy when prescribing, dispensing, and administrating DEMEROL Oral Solution to avoid dosing errors due to confusion between mg and mL, and with other Meperidine Hydrochloride Oral Solutions of different concentrations, which could result in accidental verdose and death. Ensure the proper dose is communicated and dispensed. When writing prescriptions, include both the total dose in mg and the total dose in volume. Do not use household teaspoons or tablespoons to measure DEMEROL Oral Solution, as using a tablespoon instead of a teaspoon could lead to overdosage. Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals. Dilute each dose of DEMEROL oral solution in one-half glass of water because the undiluted solution may exert a slight topical anesthetic effect on mucous membranes. Initiate the dosing regimen for each patient individually; taking into account the patient’s severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse.
Initiate treatment with DEMEROL Tablets or Oral Solution in a dosing range of 50 mg to 150mg orally, every 3 or 4 hours as needed for pain.
Initiate treatment with DEMEROL Tablets or Oral Solution in a dosing range of 1.1 mg/kg to 1.8mg/kg orally, up to the adult dose, every 3 or 4 hours as necessary.
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- Patients who are hypersensitive to the active substance meperidine or other opioid analgesics or to any ingredient in the formulation. For a complete listing, see the DOSAGE FORMS, COMPOSITION AND PACKAGING section of the Product Monograph.
- In patients with known or suspected mechanical gastrointestinal obstruction (e.g., bowel obstruction or strictures) or any diseases/conditions that affect bowel transit (e.g., ileus of any type).
- Patients with suspected surgical abdomen (e.g., acute appendicitis or pancreatitis). The administration of DEMEROL or other narcotics in patients with acute abdominal conditions may obscure the diagnosis or clinical course.
- Patients with mild pain that can be managed with other pain medications.
- Patients with acute or severe bronchial asthma, chronic obstructive airway, status asthmaticus, substantially decreased respiratory reserve; hypoxia, elevated carbon dioxide levels in the blood, cor pulmonale and other preexisting respiratory depression. In such patients, even usual therapeutic doses of opioids may decrease respiratory drive while simultaneously increasing airway resistance to the point of apnea.
- Patients with acute alcoholism, delirium tremens, and convulsive disorders.
- Patients with severe CNS depression, increased cerebrospinal or intracranial pressure, and head injury. The respiratory depressant effects of DEMEROL and its capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury,other intracranial lesions, or a preexisting increase in intracranial pressure. Furthermore, narcotics produce adverse reactions which may obscure the clinical course of patients with head injuries.
- Patients taking monoamine oxidase (MAO) inhibitors (or within 14 days of such therapy).Therapeutic doses of DEMEROL have occasionally precipitated severe, unpredictable, and sometimes fatal reactions in patients who have received MAOIs within the previous 14 days.The mechanism of these reactions is unclear, but may be related to a pre-existing hyperphenylalaninemia. Some cases have been characterized by coma, severe respiratory depression, cyanosis and hypotension, and have resembled acute opioid overdose. Other cases have resembled serotonin toxicity; predominant manifestations have included hyperexcitability, agitation, convulsions, diarrhea, tachycardia, sweating, tremor, impaired consciousness, hyperpyrexia and hypertension.
Common side effects
Demerol might cause the following side effects listed below:
loss of appetite,
urinating less than usual,
loss of interest in sex.
serious side effects
Stop using Demerol if u have the following sides effect below:
Trouble breathing, shallow breathing, or stopping breathing
Very low blood pressure, slow heartbeat, and shock
Dosing errors can result in accidental overdose and death. Avoid dosing errors that may result from confusion between mg and mL and confusion with meperidine solutions of different concentrations, when prescribing, dispensing, and administering DEMEROL Oral Solution. Ensure that the dose is communicated clearly and dispensed accurately.
DEMEROL poses risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Each patient’s risk should be assessed prior to prescribing DEMEROL, and all patients should be monitored regularly for the development of these behaviors or conditions. DEMEROL should be stored securely to avoid theft or misuse.
DEMEROL must be swallowed whole. Cutting, breaking, crushing, chewing, or dissolving DEMEROL can lead to dangerous adverse events including death
Concerns about abuse, addiction, and diversion should not prevent the proper management of pain.
Healthcare professionals should contact their State Professional Licensing Board or State Controlled Substances Authority for information on how to prevent and detect abuse or diversion of this product. Interactions with Alcohol and Drugs of Abuse
Meperidine may be expected to have additive effects when used in conjunction with alcohol, other opioids, or illicit drugs that cause central nervous system depression. more Info ;
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