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Buy Xanax 2mg Online and follow the Dosage and Administration below;
Buy Xanax 2mg Online the optimum dose should be individualized, based upon the severity of the symptoms and individual patient response. The usual dose will meet the needs of most patients. Buy Xanax 2mg Online in patients who require higher doses, the dosage should be increased cautiously to avoid adverse effects. In general, patients who have not previously received psychotropic medications will require somewhat lower doses than those previously treated with minor tranquilizers, antidepressants or hypnotics. Buy Xanax 2mg Online it is recommended that the general principle of using the lowest effective dose be followed, especially in elderly or debilitated patients to preclude the development of ataxia or oversedation.
Indication or population: Buy Xanax 2mg Online usual starting dosage (if side effects occur dose should be lowered). Buy Xanax 2mg Online usual dosage range.
Anxiety: 0.25 to 0.5 mg, given three times daily. 0.5 to 4.0 mg daily, given in divided doses
Depression: 0.5 mg, given three times daily 1.5 to 4.5 mg daily, given in divided doses.
Geriatric patients or in the presence of debilitating disease 0.25 mg, given two to three times daily 0.5 to 0.75 mg daily, given in divided doses; to be gradually increased if needed and tolerated.
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XANAX Tablets are contraindicated in patients with known sensitivity to this drug or other benzodiazepines. XANAX may be used in patients with open-angle glaucoma who are receiving appropriate therapy but is contraindicated in patients with acute narrow-angle glaucoma.
XANAX is contraindicated with ketoconazole and itraconazole since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A).
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Dependence And Withdrawal Reactions, Including Seizures
Certain adverse clinical events, some life-threatening, are a direct consequence of physical dependence to XANAX. These include a spectrum of withdrawal symptoms; the most important is seizure (see Drug Abuse And Dependence). Even after relatively short-term use at the doses recommended for the treatment of transient anxiety and anxiety disorder (ie, 0.75 to 4.0 mg per day), there is some risk of dependence. Spontaneous reporting system data suggest that the risk of dependence and its severity appear to be greater in patients treated with doses greater than 4 mg/day and for long periods (more than 12 weeks). However, in a controlled postmarketing discontinuation study of panic disorder patients, the duration of treatment (3 months compared to 6 months) had no effect on the ability of patients to taper to zero doses. In contrast, patients treated with doses of XANAX greater than 4 mg/day had more difficulty tapering to zero doses than those treated with less than 4 mg/day.
Relapse or return of illness was defined as a return of symptoms characteristic of panic disorder (primarily panic attacks) to levels approximately equal to those seen at baseline before active treatment was initiated. Rebound refers to a return of symptoms of panic disorder to a level substantially greater in frequency, or more severe in intensity than seen at baseline. Withdrawal symptoms were identified as those which were generally not characteristic of panic disorder and which occurred for the first time more frequently during discontinuation than at baseline.
In a controlled clinical trial in which 63 patients were randomized to XANAX and where withdrawal symptoms were specifically sought, the following were identified as symptoms of withdrawal: heightened sensory perception, impaired concentration, dysosmia, clouded sensorium, paresthesias, muscle cramps, muscle twitch, diarrhea, blurred vision, appetite decrease, and weight loss. Other symptoms, such as anxiety and insomnia, were frequently seen during discontinuation, but it could not be determined if they were due to return of illness, rebound, or withdrawal.
In two controlled trials of 6 to 8 weeks duration where the ability of patients to discontinue medication was measured, 71%-93% of patients treated with XANAX tapered completely off therapy compared to 89%-96% of placebo-treated patients. In a controlled postmarketing discontinuation study of panic disorder patients, the duration of treatment (3 months compared to 6 months) had no effect on the ability of patients to taper to zero doses.
Risk of Fetal Harm
Benzodiazepines can potentially cause fetal harm when administered to pregnant women. If XANAX is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus. Because of experience with other members of the benzodiazepine class, XANAX is assumed to be capable of causing an increased risk of congenital abnormalities when administered to a pregnant woman during the first trimester. Because the use of these drugs is rarely a matter of urgency, their use during the first trimester should almost always be avoided. The possibility that a woman of childbearing potential may be pregnant at the time of the institution of therapy should be considered. Patients should be advised that if they become pregnant during therapy or intend to become pregnant they should communicate with their physicians about the desirability of discontinuing the drug.
As with other psychotropic medications, the usual precautions with respect to the administration of the drug and size of the prescription are indicated for severely depressed patients or those in whom there is reason to expect concealed suicidal ideation or plans. Panic disorder has been associated with primary and secondary major depressive disorders and increased reports of suicide among untreated patients.
Episodes of hypomania and mania have been reported in association with the use of XANAX in patients with depression.
Alprazolam has a weak uricosuric effect. Although other medications with weak uricosuric effects have been reported to cause acute renal failure, there have been no reported instances of an acute renal failure attributable to therapy with XANAX. More about Xanax click here.
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